Search on: 2-OXOISOVALERATE DEHYDROGENASE (ACYLATING) 
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Descriptor English:   2-Oxoisovalerate Dehydrogenase (Acylating) 
Descriptor Spanish:   2-Oxoisovalerato Deshidrogenasa (Acilante) 
Descriptor Portuguese:   2-Oxoisovalerato Desidrogenase (Acilante) 
Tree Number:   D08.811.682.657.350.825
Definition English:   An NAD+ dependent enzyme that catalyzes the oxidation 3-methyl-2-oxobutanoate to 2-methylpropanoyl-CoA. It plays a role in the degradation of VALINE; LEUCINE; and ISOLEUCINE. 
History Note English:   2006(1980); use AMINO ACIDS, BRANCHED-CHAIN 1979, & KETO ACIDS & VALERATES 1973-1979 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   50621 
Unique Identifier:   D050645 

Occurrence in VHL:
 

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